Treatment of fatty liver

  General Treatment Fatty liver is the excessive accumulation of fat in the liver. Once you have fatty liver, how should you deal with it?  1. Find out the cause of the disease and take targeted measures. For example, those who drink a lot of alcohol for a long time should stop drinking. Excess nutrition, obese people should strictly control the diet, so that the physical ability to restore normal. Diabetic patients with fatty liver should actively and effectively control blood sugar. Patients with malnutrition fatty liver should increase nutrition appropriately, especially the intake of protein and vitamins. In short, remove the cause of the disease is conducive to cure fatty liver.  2, adjust the diet structure, advocate high protein, high vitamin, low sugar, low fat diet. Do not eat or eat less animal fat, sweet food (including sugary drinks). Eat more green vegetables, fruits and fiber-rich foods, as well as lean meat, river fish and soy products with high protein, no snacks, and no extra meals before bedtime.  3, appropriate to increase exercise to promote the consumption of body fat. Run every day, at least 6 km per hour to achieve weight loss. Sit-ups or fitness equipment exercise are very beneficial.  4, medication-assisted treatment, fatty liver is not terrible, early detection of active treatment, generally can be cured, and does not leave sequelae. It is worth pointing out that the prevention of fatty liver should start with children, especially only children, what they want to eat, what they want to give, and less activity, once they become “little fat dun”, fear of fatty liver has been.  Treatment of liver fibrosis Anti-hepatic fibrosis: drugs such as retinoic acid (retinoic acid), interferon, proline analogs, proline hydroxylase inhibitors and colchicine intervene in at least one or several steps of the collagen production process. Vitamin A preparations such as retinoic acid and beta carotene have therapeutic potential. There are three types of interferons, α, β and γ. Currently, α and γ interferons are considered to have significant anti-fibrotic effects on the liver, and γ interferon has the strongest anti-fibrotic effect. Therefore, the use of interferon in patients with compensated cirrhosis may lead to a decompensated state. Currently, interferon is mainly used in the treatment of chronic viral hepatitis in its active phase to balance antiviral and anti-fibrosis, and its application is not advocated after it has progressed to decompensated cirrhosis; colchicine can act on different stages of collagen chain reaction, but large-scale clinical studies with colchicine for the treatment of patients with cirrhosis have not been successful, and it is not significantly better than Adrenocorticotropic hormone can inhibit collagen synthesis and can inhibit collagenase activity to promote collagen degradation, but the long-term application of these drugs has serious side effects and reduces the immunity of the body, so it is difficult to be clinically recommended for the treatment of liver fibrosis; hepatocyte growth factor can stimulate collagenase activity to promote collagen degradation, and can inhibit the overexpression of TGF-β gene, as well as inhibit hepatocyte apoptosis, thus It acts as an anti-fibrotic agent. In addition, it can mobilize fat and potentially reduce the degree of fatty liver, but its clinical efficacy needs to be further verified.  So far, there is no effective drug for prevention and treatment of fatty liver in western medicine, and the best treatment is long-term regulation by Chinese medicine. It is good to use some specialized drugs containing turmeric and other herbal ingredients, such as Gambel. Chinese herbal medicine is best with he shou wu and hawthorn, both of which can lower blood lipids and prevent cholesterol deposition in the liver. Western medicine is often used to protect liver cells, de-lipidizing drugs and antioxidants, such as vitamins B, C, E, lecithin, ursodeoxycholic acid, silymarin, inosine, coenzyme A, reduced glutathione, taurine, carnitine orotate, hepatic tylenol, and certain lipid-lowering drugs (e.g. hepatic key clear), etc. Although there are many of these drugs, most of them need further verification of their efficacy and safety, so they should be used properly under the guidance of a doctor and should not be abused. But in general, if it is only fatty liver, not hepatic encephalopathy, the above drugs vitamin B, C, E, lecithin, inosine, coenzyme A, reduced glutathione, taurine, carnitine orotate and other vitamins and endogenous amino acid drugs are very safe, and will not rebound after stopping the drugs like biphenyldiphenhydramine.  Exercise therapy 1, exercise misconceptions to correct: “fatty liver is eaten out, more exercise, less diet, natural will be good”, this crude concept seems to be understood by everyone. As a result, some misconceptions have emerged. Such as: “I move every day, I do all the housework”; “usually I do not have time, I will go to the fitness center on holidays to exercise a half day”; “I have a lot of work every day, I have enough to consume, no need to make Other exercises” and so on. In fact, the appropriate exercise according to the specific circumstances of the patient to develop an exercise treatment program.  2, specific treatment: the specific circumstances of the patient include: gender, age, weight, the size of the usual activity, the conditions of the exercise site, the specificity of the work and whether accompanied by other diseases and so on. For example, it is generally appropriate to take a walk after a meal, but for some patients it may not be appropriate; for some patients with degenerative joint disease of the lower limbs, it is not appropriate to choose exercises like jogging, ladder climbing and other exercises with greater joint mobility; the same age and other health conditions of young and strong men and women, due to differences in gender and body type, the amount of exercise given should also be different, which is why in the treatment of fatty liver must be By the professional physician according to the specific circumstances of the patient to make a comprehensive assessment after making the appropriate guidance.  3. Exercise also needs to be prescribed: therapeutic exercise requires a scientific exercise prescription after an objective and comprehensive assessment of the patient by a gastroenterologist and a rehabilitation physician according to the patient’s specific situation, with specific quantitative indicators in terms of exercise methods, time, intensity, frequency and volume, followed by a phased assessment of the patient’s adaptability and efficacy, and continuous adjustment and improvement. Each exercise program has a different quantitative index and produces a different “oxygen consumption”. Your exercise prescription will be tailored to your needs.  The formulation of the exercise prescription should be suitable for the specific situation of the patient, but also to grasp the appropriate “oxygen consumption”, so as to achieve both reasonable, but also scientific and safe standards.  4, moderate exercise instead of drugs; strongly recommended: fatty liver treatment 3 key, which items are suitable for you? The whole-body low-intensity dynamic exercise aimed at exercising the whole body strength and endurance, i.e. aerobic exercise, such as jogging, medium and fast walking (115-125/min), cycling, going up and down stairs, climbing, playing badminton, playing shuttlecock, patting leather ball, dancing, radio gymnastics, rope skipping and swimming, etc., can make the sympathetic nerve excited, plasma insulin decrease, while catecholamine, glucagon and growth hormone secretion increase, inhibit the synthesis of triglycerides and promote lipolysis.  The exercise program for patients with fatty liver should be based on low-intensity, prolonged aerobic exercise. Powerful activities characterized by aerobic metabolism are more effective for fatty liver patients to lower fat and promote fat loss in the liver.  How long do you want to practice? The duration of exercise with high intensity should be short, but if the intensity is low, the duration should be long, and the time and intensity should be considered according to the life background and obesity level of fatty liver patients. The amount of exercise is gradually increased and made constant, orderly and moderate, and the prescribed exercise targets must be completed at each exercise.  Take walking as an example, we can gradually increase from 5,000 steps/day to 7,000-10,000 steps, and then walk at a fast pace to increase the amount of exercise in stages; we can follow the principle of “3, 5, 7”, that is, 3,000 meters per day (within 30 min), 5 times per week, and the sum of pulse rate and age after each walk is 170.  Diet therapy 1, control calorie intake, so that the fat oxidation consumption in the liver cells. Obese people should gradually lose weight to bring it down to within the standard weight range. In terms of standard weight, 84 to 105 kJ (20 to 25 kcal) of caloric energy can be given per kg of body weight. Standard weight (kg) = length (cm) – 105 (or 100), men over 165 cm minus 105, while women and men under 165 cm minus 100. 2, limit fat and carbohydrate intake, according to the standard weight per kilogram of body weight can be given 0.5 to 0.8 grams of fat per day, it is appropriate to use vegetable oils or foods containing long-chain unsaturated fatty acids, such as fish, etc.. Carbohydrates can be given 2 to 4 grams per kilogram of body weight per day, and the intake of edible sugar should not be excessive.  3, high protein diet, 1.2 to 1.5 grams per kilogram of body weight per day can be given, high protein can protect liver cells and promote the repair and regeneration of liver cells. Protein supply, high-quality protein should take up an appropriate proportion, such as tofu, bean curd and other soy products, lean meat, fish, shrimp, skim milk, etc.  4, to ensure the supply of fresh vegetables, especially green leafy vegetables, to meet the body’s need for vitamins. However, do not eat too many vegetables and fruits containing sugar.  5, drink an appropriate amount of water to promote the body’s metabolism and excretion of metabolic waste.  6, foods rich in methyl sulfur amino acids, such as millet, oat noodles, sesame, rape, spinach, cauliflower, beet, sea rice, dried scallops, tamari and other foods can promote the synthesis of phospholipids in the body and assist in the transformation of fat in liver cells.