IgA nephropathy Oxford Pathological Typing

  Oxford staging pathology staging report form Contents include 4 pathological indicators that independently affect prognosis: thylakoid proliferation (M0/1) endothelial cell proliferation (E0/1) segmental sclerosis or adhesions (S0/1) tubular atrophy or interstitial fibrosis (T0/1/2) Pathological indicators Definition Points Thylakoid proliferation score (M) <4 thylakoid cells/ thylakoid zone = 0 M0: ≤0.5 4-5 M1: >0.5 6-7 thylakoid cells/thylakoid zone = 2 >8 thylakoid cells/thylakoid zone = 3 Thylakoid cell proliferation score averaged over all glomeruli Intracapillary proliferative lesion (E) Glomerular intracapillary cell proliferation resulting in collateral narrowing E0: no E1: yes Segmental sclerosis and adhesions (S) Any variable degree of collateral involvement S0: no S1: yes  Interstitial fibrosis or tubular atrophy (T) Renal cortical tubular atrophy or interstitial fibrosis T0: 0%-25% T1: 26%-50% T2: >50% At the same time, to reflect the acute and chronic renal lesions, the number of glomeruli and some quantitative pathological indicators including the proportion of cellular or cellular fibrous crescent, the proportion of fibrinoid necrosis, the proportion of endothelial cell proliferation and the proportion of glomerular sclerosis as additional The report must also be issued.