Diagnosis of symptoms of fine reticulate to patchy hyperpigmentation

  Pigmented spots are fine mesh to patchy, initially light red. Later it turns to greenish gray to dark brown, mostly on exposed areas such as cheeks, back of the neck, especially around the eyes and temporo-zygomatic areas.  It can be seen in congenital dyskeratosis, which is visible in the upper part of the trunk, neck, shoulders, face and abdomen as a distinct fine reticulated gray-brown pigmentation with a velvety feel. Also visible is skin atrophy, very pronounced capillary dilation, as if vascular atrophic skin heterochromia. The skin on the face is red and atrophic, and there may be irregular patches of pigmentation, extensive atrophy of the dorsal skin of the hands and feet with transparent shine, diffuse keratotic damage on the palms, metatarsals, knees and elbows, etc. The skin of the whole body is prone to form large blisters after trauma. Patients may sometimes have atrophic deformity changes of the skin, muscles and bones of the hands and feet.  Fine reticulate to patchy hyperpigmentation is usually accompanied by three features: ① methyl dystrophy and failure to form nail plates.  (ii) There may be white thickening of the oral, inter or vaginal mucosa (white keratosis).  (iii) The skin may have extensive reticulopigmentation and depigmented areas like vascular atrophy skin heterochromia, but it is mild.  Livedo reticularis is a rare functional cutaneous vasospastic disease characterized by persistent, symmetrical reticular or patchy cyanosis of the skin of the limbs and/or trunk. Its etiology is not yet clear. It is most often seen in normal children and young women. The incidence is similar in both sexes, but symptomatic women are more common. There are no seasonal differences.