How long you can live with a heart clot depends on the underlying disease of the heart. For example, atrial fibrillation, commonly known as atrial fibrillation caused by wall thrombosis, only need to take long-term anticoagulant drugs to prevent the thrombus from dislodging and causing brain embolism or other organ embolism can be, generally does not have a great impact on life expectancy. If the thrombus is caused by dilated cardiomyopathy or heart failure, the life expectancy depends entirely on the underlying disease. If there is thrombus, anticoagulation therapy is needed, and in some patients the thrombus can disappear completely after 3 months of anticoagulation therapy.