It is recommended to go to a regular hospital for examination, which can effectively reduce the chance of HIV infection. HIV exists in the blood, semen, vaginal secretions, cerebrospinal fluid, thoracoabdominal fluid, amniotic fluid and breast milk of HIV-infected patients, and can be transmitted through sexual contact, blood and blood products or mother-to-child transmission. After the colonoscopy, if the treatment is not timely, it can aggravate the disease and may lead to serious complications, therefore, patients should promptly undergo antiviral treatment, commonly used drugs for the treatment of AIDS are entry cell inhibitors, reverse transcriptase inhibitors, HIV integrase inhibitors, etc. In addition, patients should have regular follow-up examinations at the hospital to monitor HIV antibodies and CD4 lymphocytes. Because HIV is prone to drug resistance, it is important to change treatment regimens as soon as antiviral drug resistance occurs.