Lactobacillus is a kind of bacteria in the vagina, and it exists as a kind of dominant bacteria, which helps to maintain the acidic environment of the vagina and can play the role of vaginal self-cleaning. If broad-spectrum antibiotics are abused, it will inhibit the growth of lactobacilli, and the gynecological examination may show that there is no lactobacilli in vaginal secretion. Estrogen can be appropriately supplemented, such as dextran, which can help the growth of lactobacilli; 3, vaginal inflammation: if due to long-term use of strong alkaline detergent to wash the pubic area, or taking broad-spectrum antibiotics, it will inhibit the reproduction of lactobacilli, so that other pairs of antibacterial or mycobacteria proliferate, resulting in bacterial vaginitis, vulvovaginal pseudomycosis and other vaginal inflammation, which can further inhibit the growth of lactobacilli, so there may be gynecological In this case, it is necessary to use potassium permanganate sitz bath for vaginal inflammation, clotrimazole suppositories, metronidazole, tinidazole and other medications to inhibit the proliferation of harmful bacteria, which can gradually restore lactobacilli.