When changing medicine with Chinese medicine, the following matters should be noted: first of all, the action should be gentle and not too hard to avoid unnecessary damage to the wound. It is also important to choose different topical drugs according to the specific situation of the wound, which is also the characteristic of Chinese medicine. For wounds with a lot of exudate, it is not advisable to use ointment, but bulking agents to avoid impregnating the skin with exudate that does not flow easily. In the early stage of trauma, the wound needs to be changed once a day or even twice a day to keep the wound clean. In the later stage, the main focus is to promote the growth of granulation, and the medication can be changed once every two days or more. In order to keep the environment around the ulcerated surface clean and eliminate pathogenic microorganisms, it is advisable to remove scales and nail fungus, and also to use a topical wash with triple yellow lotion, or topical application of Neosporin tincture, iodophor, etc. In order to prevent further expansion of the ulcerated surface of the affected toe and to control the inflammatory reaction around the ulcerated surface, Yunnan Baiyao alcohol is often used clinically to dress the area around the wound. In order to prevent necrosis of the affected toe, it is necessary to isolate each toe of the affected toe when changing the medication, and use the powder for those who are not ulcerated, and use 0.5% metronidazole liquid gauze dip and squeeze dry to separate the bandage for those who are ulcerated.