Stomach pain and diarrhea may be caused by acute gastroenteritis or chronic gastric diseases combined with chronic intestinal diseases, etc. Antibiotics, drugs that inhibit gastric acid secretion and protect the gastrointestinal mucosa can be used. 1. Acute gastroenteritis: Bacterial, viral and other microbial infections, as well as drugs and alcohol and other triggers, may lead to acute gastroenteritis symptoms of stomach pain and diarrhea. If it is caused by bacterial infection, you can take gentamicin, levofloxacin and other antibiotics. There is no specific treatment drug for gastroenteritis caused by viral infection. You can take montelukast to protect the intestinal mucosa; you can take omeprazole to inhibit the secretion of gastric acid for stomach pain. 2. Chronic gastric diseases combined with chronic intestinal diseases: when chronic gastritis, gastric ulcer and other chronic gastric diseases combined with ulcerative colitis, chronic colitis and other chronic intestinal diseases, due to gastrointestinal mucosal congestion and edema, may also appear stomach pain and diarrhea symptoms. You can take omeprazole, aluminum sulfate and other drugs to inhibit gastric acid secretion and protect the gastric mucosa and treat the symptoms of stomach pain. Antibacterial drugs such as sulfasalazine and mesalazine can be used to treat diarrhea. If the symptoms of stomach pain and diarrhea occur, it is not recommended to take medication on your own. It is recommended to go to the hospital to check the gastroscopy, enteroscopy, blood routine, stool routine items in the doctor’s guidance under the guidance of drug treatment.