Isolated liver metastatic cancer, such as colorectal and other tumors, if the metastatic lesions are relatively small, chemotherapy is given first, followed by an evaluation to see if surgery is possible, which is currently recommended at the 2C level. However, there are some cases in which surgery cannot be performed, such as tumor size or location limitation, multiple lesions or insufficient liver reserve function, etc. Local non-surgical treatment can be performed. Ablation: mainly for those who are not capable of surgical resection or those who are not allowed to have surgery, local treatment can be preferred, even without considering chemotherapy first (no chemotherapy is recommended at Grade 2C), mainly applying radiofrequency ablation technology radiofrequency ablation (RFA) Recommendation Grade 1B. For tumors smaller than 5 cm, three For lesions less than 5 cm, three or more lesions that are not close to large blood vessels, it is more suitable. The effect of hepatic arterial perfusion chemotherapy is not yet easy to assess, and in general, if chemotherapy is needed, systemic chemotherapy is directly recommended. 3. The effect of radioembolization technique and systemic chemotherapy can not be assessed at present, and systemic chemotherapy is recommended. 4.Radiation therapy, general external irradiation for liver tumor treatment is limited because of the big side effects, and more researches are conducted on stereotactic radiotherapy (SBRT), and it is reported that the control rate of 2 years can reach more than 90%, which is the result of the clinical research of phase 1 and phase 2, and the safety is reported to be still good. Specific program development requires multidisciplinary expert consultation to give the best treatment choice.