Also known as ichthyotic nevus, it is essentially a type of common wart that is caused by a human papilloma virus infection. Therefore, patients can remove it through general treatment, medication and physical therapy under the guidance of doctors. 1. General treatment: Because ichthyosis naevus is caused by viral infection, it is infectious. It is suggested that patients should iron and disinfect shoes and socks, personal clothes and bed sheets and covers to reduce local friction and stimulation, so as to prevent themselves from infecting or infecting others. 2. Medication: Patients can use antiviral creams such as imiquimod cream and recombinant human interferon α2b gel under doctor’s guidance. Patients can also take oral medication to improve immunity, such as thymidine enteric-coated tablets and splenic peptide lyophilized powder. 3. Physical therapy: patients can also be treated by electrocautery, laser therapy or liquid nitrogen freezing under the guidance of doctors. For patients with ichthyosiform nevus on the feet, it is recommended to go to regular hospitals for timely examination and standardized treatment under the guidance of professional doctors.