Foreign body sensation when closing the eyes may be caused by conjunctivitis and keratitis, dry eye or conjunctival corneal foreign body. 1. Conjunctivitis and keratitis: Inflammatory lesions of the eye surface, resulting in conjunctival congestion and edema, which will make the patient feel obvious foreign body sensation when he closes his eyes, and he needs to follow the doctor’s instructions and timely anti-infective treatment, for example, he needs to use levofloxacin eye drops or ophthalmic ointment with ofloxacin and so on. 2. Dry eye: patients look at the cell phone and computer for a long time, resulting in visual fatigue of the eyes, leading to eye dryness, which can also lead to a decrease in the stability of the tear film, conjunctival, corneal dryness, so closing the eyes will be accompanied by the symptom of foreign body sensation. Follow the doctor’s prescription of local point artificial tears for treatment. 3. Conjunctival corneal foreign body: generally caused by small insects, gray foam, wood chips and metal shavings into the cornea, the patient in the eyes after closing the foreign body sensation. For superficial corneal foreign body, can be under surface anesthesia with saline wet swabs. For deeper foreign bodies, a sterile needle can be used to remove them. If the foreign body is large and has partially penetrated the cornea into the anterior chamber, microsurgery should be performed to remove the foreign body, which can effectively remove the intracorneal foreign body. In summary, if you have a foreign body sensation when you close your eyes and the cause is unknown, it is recommended that you consult the ophthalmology department of the hospital in a timely manner. Do not delay the condition.