Late-onset encephalopathy of acute carbon monoxide poisoning, also known as acute carbon monoxide poisoning follow-up disease, post-onset disease, sequela, etc., refers to patients with acute carbon monoxide poisoning, conscious, after a period of pseudo-healing, the sudden onset of dementia, psychiatric symptoms and extrapyramidal system-based neurological disorders. The pathogenesis of this disease is still unclear, and there are generally the following doctrines. I. Conventional treatment: 1. Increase cerebral blood flow and improve cerebral blood circulation (1) blood thinning therapy with intravenous low molecular dextrose anhydride can expand blood volume and thin the blood; (2) vasodilator drugs such as nicotinic acid, cornusine, chuanxiongxizine, sodium bicarbonate, hexetone cocaine, betadine hydrochloride, cyclobenzaprine (anti-embolism pills), Vibramycin, haitechen, compound danshen tablets, and gerberellic acid tablets. Oxygen with 3%~5% carbon dioxide can also be inhaled. 2.Anti-coagulation therapy There is no consensus on the use of anticoagulants. 3, inhibit platelet aggregation drugs Pansentin, aspirin, Polivir, etc. can inhibit platelet aggregation, prevent and reduce thrombosis. 4, brain cell excipients and brain cell metabolism promoter brain fukang, brain fuxin, adenosine triphosphate, cytochrome C, coenzyme A, r-amyl casein, and so on. 5.Anti-shock paralyzing drugs Amantadine, Antan, levodopa side effects are relatively large at present, rarely used, the United States because of the system of levodopa and dopamine decarboxylase inhibitor of the composite drug and its side effects are reduced, for patients with high dystonia can be used. 6.Skeletal muscle relaxants 7.Chinese traditional Chinese medicine 8.on the use of hormones on the adrenal cortical hormone efficacy has not yet gained a unanimous opinion. A lot of clinical research is in progress. Hyperbaric oxygen therapy: 1, hyperbaric oxygen therapy can improve the partial pressure of blood oxygen and increase the oxygen storage capacity of brain tissue; 2, hyperbaric oxygen increases the dispersion distance of oxygen and improves the oxygen supply capacity of brain tissue; 3, increase the aerobic oxidation of brain tissue, increase cellular energy and accelerate the repair of brain tissue; 4, promote the establishment of collateral circulation in brain tissue and the neonatalization of capillaries to improve the blood supply of brain tissue; 5, hyperbaric oxygen body fluids and immunity function is reduced; 6, hyperbaric oxygen body fluids and immunity function is reduced; 6, hyperbaric oxygen body fluids are not used to improve the blood supply of brain tissue. Decrease in immune function; 6, accelerate nerve fiber myelin regeneration.