Delayed encephalopathy of carbon monoxide poisoning can be handled by drug treatment, hyperbaric oxygen therapy and life care. 1. Pharmacological treatment: patients can be treated with intravenous suxunin injection and dextrose 40 glucose injection to improve blood circulation and expand blood volume; intravenous olaxetan injection can also be used to nourish the brain nerves; when accompanied by increased muscle tone, the muscle relaxant ethylpiperidinone can be used; when accompanied by tremor, phenazopyridine can be used. 2. Hyperbaric oxygen therapy: patients can be treated with hyperbaric oxygen therapy, which can promote the recovery of brain tissue. 3. Life care: the diet should be balanced and nutritious, and attention should be paid to supplementing vitamins and trace elements. For patients who have difficulty in eating, nasal feeding should be given; for patients who cannot take care of themselves, family members should change clothes in time to prevent complications such as colds and infectious diseases; for bedridden patients, joint mobilization exercises should be carried out to promote recovery. It is recommended that patients with delayed encephalopathy in carbon monoxide poisoning should consult a doctor for timely examination and treatment under the guidance of a doctor to avoid delaying their condition. All drugs should be used under the guidance of a doctor.