Mushrooms are commonly known as mushrooms. It is a class of higher fungi. It has high food value and some of them can be used medicinally. However, some mushrooms contain toxins, which may cause poisoning if eaten accidentally. Therapeutic measures should be used in a timely manner to induce vomiting, gastric lavage, diarrhea, enema and other methods in order to quickly eliminate the poison that has not yet been absorbed. Especially for those who accidentally eat poisonous umbrella, white umbrella and other poisonous mushrooms, the onset of the disease should have been more than 6 hours from eating mushrooms. However, it is still advisable to give gastric lavage, diarrhea and other treatments. Gastric lavage and enema followed by the introduction of tannic acid and activated carbon can reduce the absorption of toxins. Other treatments include: 1. Atropine is mainly used for muscarinic poisoning. According to the severity of the disease, 0.5 ~ 1mg subcutaneous injection, every 1/2 ~ 6 hours. If necessary, the dose can be increased or switched to intravenous injection. Atropine is also used to relieve gastrointestinal symptoms such as abdominal pain and vomiting and diarrhea. It also has a role in atrioventricular block due to toxic myocarditis. 2, mercapto antidote poisonous umbrella, white umbrella and other toxic mushrooms poisoning with atropine treatment is often ineffective. Zhongshan Hospital of Shanghai Medical University has used antidotes containing sulfhydryl groups to treat this kind of muscular poisoning, and there is a certain effect. Its mechanism of action may be that this kind of drugs and some toxins such as poisonous umbrella peptide (amanitin) and so on, blocking its molecular sulfur sparing bond, so that its toxicity is weakened, and protect the activity of sulfhydryl enzyme in the body, and even restore part of the enzyme has been combined with the toxin of the vitality of the enzyme. Adrenocorticotropic hormone is suitable for hemolytic muscarinic poisoning and other severe poisoning cases, especially for cases with toxic myocarditis, toxic encephalitis, severe liver damage and bleeding tendency. Symptomatic treatment For the gastroenteritis stage of all types of poisoning, fluids should be actively infused to correct dehydration, acidosis and electrolyte disorders. For those with liver damage, hepatoprotective supportive therapy should be given. For those with mental symptoms or convulsions, sedation or anticonvulsant therapy should be given. And may try dehydration agent.