Some antibiotics, hypoglycemic drugs and other toxic reactions with alcohol, it is recommended that during the medication as well as within two weeks of stopping the medication do not drink alcohol, otherwise, it may be life-threatening. 1, antibacterial drugs cephalosporins such as cefoperazone, cephalosporin, cefmetazole, cefamandole, cefmenoxime, cefotiam, as well as metronidazole, tinidazole, furazolidone and so on can cause disulfide wake-up reaction, manifested in the use of alcohol after the use of drugs to appear limb weakness, weakness, drowsiness, vertigo, hallucinations, headache, nausea, vomiting, chest tightness, generalized redness, weakness, convulsions, or even a drop in blood pressure, respiratory depression, shock and so on. Reaction. In mild cases, it can be relieved on its own, but in severe cases, necessary measures should be taken in time to save the patient. Therefore, patients should abstain from drinking alcohol for 2 days before using the above drugs, and avoid drinking alcohol and taking ethanol-containing beverages and medicines for 1 week after the use of the drugs. Toluenesulfonylurea and chlorosulfopropylurea can also cause these reactions. It is recommended not to drink alcohol during the medication and within two weeks after stopping the medication. 2. Morphine ethanol will produce synergistic effect when combined with morphine. It may cause poisoning and even death. 3, sedative-hypnotic drugs diazepam, nitrazepam, clonazepam, triazolam, barbiturates and chloral hydrate and other sedative-hypnotic drugs, combined with ethanol can cause drowsiness, trance, coma, respiratory failure, and even death. 4, antipyretic and analgesic aspirin, ibuprofen, diclofenac, etc., if you take the drugs when drinking a lot of alcohol, can make the gastrointestinal mucosa by the double stimulation of drugs and ethanol, and even cause peptic ulcers or bleeding. 5, glucose-lowering drugs glibenclamide, metformin, insulin, etc. Large amounts of alcohol during the drug can cause dizziness, panic, cold sweats, hand shaking and other hypoglycemic reactions, severe hypoglycemic coma can occur. 6, antiepileptic drugs long-term alcohol consumption can reduce the concentration and efficacy of phenytoin sodium, but the drug at the same time a large number of alcohol can increase the blood concentration, taking sodium valproate during drinking, can enhance the central inhibition. 7, anti-anginal drugs such as isosorbide nitrate, nitroglycerin and nifedipine, etc. Drinking alcohol during the medication can cause excessive vasodilatation, resulting in severe headache, sudden drop in blood pressure and even shock. 8, blood pressure medicine nifedipine, hydrazine phenazine, dibazole, etc. and wine with the service, it is easy to appear low blood pressure. 9, anti-allergic drugs such as benadryl, chlorpheniramine, sai ganodine and so on with alcohol, can cause drowsiness, trance, coma. 10, hemostatic and anticoagulant drugs ethanol can inhibit coagulation factors, counteract the role of hemostatic drugs, so that the role of hemostatic drugs is reduced. 11, diuretics furosemide, hydrochlorothiazide, etc. can reduce blood pressure through urination, ethanol also has the role of vasodilatation, taking diuretics at the same time drinking alcohol, there may be dizziness, erectile dyskinesia and other symptoms. 12, antidepressants taking promethazine and doxepin and other antidepressants during the consumption of alcohol, can produce central tranquilizing effect.