At present, in the domestic general hospitals, the general treatment of poisoning is not yet a problem, but set up a poisoning department or occupational disease specialized departments of the hospital is less, the reason for this, mostly due to the source of disease and even get less economic benefits and so on cause hospital leaders to the lack of attention to the development of the profession. According to statistics, there are 1,462 level 3 hospitals in China, and even more below level 3. On the one hand, there are specialized prevention and treatment institutions for occupational diseases in large cities across the country, but they are more inclined to scientific research and chronic disease prevention and treatment, with a simple structure and limited technical force, while the success of clinical treatment of acute and chronic poisoning relies largely on the multi-disciplinary joint treatment capability of large comprehensive hospitals. On the other hand, many large hospitals, such as our hospital, is the poisoning and occupational diseases under the emergency center, set up as a second-level departments, but exclusive beds are few, the department of the withering of talent, most of the other professions to the profession, there are hospitals so that the department is in the embarrassing position of sharing beds with other departments. In fact, poisoning and occupational disease department is highly specialized, in the disposal of acute public health emergencies, better reflect the comprehensive treatment level of a medical institution. First, the development of China’s occupational disease history confirms its great contribution to society The beginning of the founding of the country, with the vigorous development of new China’s industry and agriculture, and with it the emergence of a large number of physical and chemical factors toxic diseases, to Premier Zhou Enlai as the representative of the country’s leaders have always attached great importance to the treatment of occupational diseases and the cultivation of professionals, has cordially received Wu Zhizhong, headed by the older generation of occupational disease specialists. 1956, Wu Zhizhong was already 50 years old. In 1956, at the age of 50, Wu Jizhong was appointed to set up China’s first Institute of Labor Hygiene and Occupational Diseases. He was engaged in clinical research on occupational diseases for a long time and made important contributions to the prevention and treatment of common occupational diseases, such as pneumoconiosis and lead poisoning, as well as the establishment of a national network for the prevention and treatment of occupational diseases. His most outstanding academic achievement was his pioneering of occupational medicine in China, editing the 1.3 million-word tome Occupational Diseases, which made great contributions to the socialist construction of new China. Subsequent generations of occupational patients have made extremely brilliant achievements for the development of the country’s economy. Shandong Province is a large industrial and agricultural province, and the efforts made by the Shandong Institute of Labor Health and Occupational Diseases and Shandong Provincial Hospital to prevent and control occupational diseases have benefited millions of workers. The development of human diseases is a process of competition between human beings and nature. They are roughly categorized into endogenous and exogenous diseases. With the development of society and progress of human beings, there are more than one million kinds of chemicals entering the human society every year, and we will face more challenges of toxic diseases. Among them, diseases caused by exogenous factors such as various poisons, radiation, etc. are widespread enough to attract the attention of every country and even all mankind. on April 29, 2008, the Ministry of Health released the results of the third national cause of death survey, which showed that in both urban and rural areas of our country, injuries and poisonings are the fifth leading cause of death after malignant tumors, cerebrovascular diseases, heart diseases and respiratory diseases, and the number of deaths of the two combined Together, they account for 10.7% of the total death rate. Among the poisoned patients in China, only the patients with occupational disease poisoning amounted to 3.7 million, and is increasing at the rate of 1 million per year, the treatment of acute poisoning has become one of the topics that clinicians must face. Second, the principles and characteristics of occupational disease treatment Many people mistakenly think that since the disease is caused by exogenous factors, it is easier to treat than its own endogenous diseases, but in fact, it is not. Toxic disease treatment highlights the word “urgent”. A significant sign of the progress of modern medicine is the improvement of the level of treatment of acute and critical patients, and at the same time to measure the overall level of medical care in a hospital is often to look at the results of the treatment of critical patients. Internationally advanced countries have established “Emergency Medical Service System (EMSS)”, which is a complete system of pre-hospital emergency care, emergency room care, and emergency ICU care. Emergency medicine is a great progress, is the inevitable trend of social development. First aid level represents the technical level of the medical unit. Toxic disease treatment principles: 1, the scene as soon as possible to remove the unabsorbed poison, blocking the continued absorption pathway of poison. Rescue treatment can be aimed at the characteristics of toxic exposure to prevent the continued absorption of poisons from the respiratory tract, digestive tract, skin and mucous membranes to start. Including the removal of skin poisons outside the hospital, a large number of water to clean the poison in the eyes, inhalation of poison first aid, ingestion of poison first aid. Such as the inhalation of poisoned patients lifted to the ventilation place to breathe fresh air, oxygen inhalation for those in a position to do so; take off all the clothes of the patients who have been absorbed through the skin; press the root of the tongue with the fingers of the patients who have been poisoned in the digestive tract or drink a lot of water to induce vomiting and other measures. 2.Prevent the absorption of poison. It refers to the professional measures such as inducing vomiting, gastric lavage and catheterization immediately after the patient is sent to the medical institution, and the treating physician needs to strictly grasp the indications and precautions. For some poisoning can be in the gastric lavage or diarrhea can be used to neutralize the toxicity of poisonous drugs, such as corrosive poison poisoning can be instilled into the egg, thick rice soup, starch paste, milk, etc., in order to protect the gastrointestinal mucosa, delay the absorption of poison; oral charcoal powder, white clay has the function of adsorption of poisons; strong acid poisoning can be used to neutralize the weak alkali (lime superscripts, suds), strong alkali poisoning can be used to neutralize the weak acid (1% acetic acid), and the daily drinking of soya bean milk, Milk or egg white also have neutralization of acid, alkali effect and protection of the gastrointestinal tract mucous membrane effect, and commonly used as a metal poison antagonist, strong tea can precipitate certain poisons. In the 2002 SARS patient treatment, there have been several patients who accidentally took acetic acid, we created a warm milk gentle gastric lavage method, greatly slowing down the gastrointestinal tract further damage. 3, to promote the discharge of the absorbed poison, refers to the application of special antidote drugs and specific treatment methods. Not all poisonings have special antidotes and specific treatment methods to cope with, but some poisonings, according to the metabolic characteristics of the poison in the treatment, can be selected to accelerate or block its continued metabolism, thus reducing the damage caused to the body. Specific treatment methods include ① diuretic detoxification: drinking a lot of water, drinking tea have diuretic detoxification effect; can also be taken orally 20 ~ 40mg/day tachycardia. ② Intravenous detoxification: 40-60ml of 5% dextrose, plus vitamin C 500mg intravenous drip. ③ Blood exchange or component transfusion detoxification: commonly used in cyanide and arsenic poisoning, the patient’s blood can be exchanged for the blood of healthy people of the same type. Hemodialysis or hemoperfusion detoxification: this method is especially suitable for the treatment of unknown poisons. Hemoperitoneal and colonic dialysis is suitable for water-soluble poison poisoning, and hemoperfusion is suitable for fat-soluble poison poisoning. 4. Symptomatic and supportive treatment. Equivalent to the internal medicine treatment of other specialties, return to the path of all internal diseases. Third, the health administration and hospital administrators should attach great importance to the development of poisoning and occupational disease specialties To some extent, it can be said that poisoning and occupational disease physicians need to have more knowledge of treatment, because the patients contacted, may be multiple organ damage. As a large general hospital, which often solves difficult cases, the specialty of poisoning and occupational diseases is an indispensable department, and of course it can also be an important part of the emergency center. However, there will probably be some chronic poisoning patients needing treatment, so hospital administrators and poisoners and occupational disease physicians should respond rationally to facilitate the development of the hospital and the construction of the discipline as a starting point, so as to correctly view the clinical status of poisoning and occupational disease specialties.