Nausea and vomiting at the onset of headache is considered to be a migraine. In migraine, patients usually have a history of recurrent headache attacks, which are usually triggered by exertion, stress, cold, or poor rest. The cause of migraine is not fully understood clinically, but it is considered to be related to genetic, endocrine, metabolic, and environmental factors. First, patients can be given non-steroidal anti-inflammatory drugs, such as acetaminophen and ibuprofen, during the acute phase of migraine attacks. Secondly, patients can also be given special analgesics, such as painkillers like treprostatin, which are commonly used in clinical practice, as well as Chinese herbal medicine, which can be administered according to the tongue and pulse. In addition, for patients with frequent migraine attacks, the patient can be given a foaming test to rule out vasospasm caused by microembolism stimulation. If microembolism is found, the patient should be given a transesophageal ultrasound if necessary to rule out congenital oval hole non-closure.