Erythrodermic psoriasis, or erythrodermic psoriasis, is one of the least common types of psoriasis and can be treated through the use of biologics. Erythrodermic psoriasis is a type of psoriasis, and the clinical manifestations often include diffuse flushing and infiltration and swelling of the skin all over the body, accompanied by a large number of furfuraceous scales, and may be self-conscious of itching and discomfort. The disease has a long course and is prone to recurrence, and can be treated with the use of biologics, such as etanercept, infliximab, and tofacitinib. In addition, medications such as methotrexate, cyclosporine, azathioprine, and leflunomide can be used to treat erythrodermic psoriasis. The use of drugs should be under the guidance of medical professionals to avoid adverse reactions.