In the physical examination report, urobilinogen is indicated as negative and positive. Normally, urobilinogen is negative or weakly positive. A positive urobilinogen, on the other hand, indicates a high level. So, what is the cause of high urobilinogen? Here’s a look. 1, liver cell damage, liver dysfunction, resulting in the destruction of red blood cells in the liver, resulting in high urobilinogen. 2, suffering from hemolytic jaundice caused by the destruction of red blood cells, resulting in high urobilinogen. Because of the inherent defects of the red blood cells themselves or exogenous damage to the red blood cells, the red blood cells are destroyed in large quantities, which leads to an increase in the production of bilirubin and urobilinogen. 3, high urobilinogen may also be caused by cardiac insufficiency, constipation, hyperthermia and other reasons. 4, portal cirrhosis, congestive heart failure and sepsis, etc. Due to liver dysfunction, urobilinogen in the urine also increases because the normal amount of urobilinogen absorbed from the intestine cannot be utilized and reexhausted via the bile duct.