It is useful to take metronidazole tablets for toothache. This is because metronidazole tablets have an anti-anaerobic bacterial infection, and when used in conjunction with anti-inflammatory drugs, they have a particular inhibitory effect on the bacteria in the mouth. Toothache usually has anaerobic bacterial infection, and will produce a large number of bacterial growth, taking metronidazole tablets together with anti-inflammatory drugs can effectively suppress the toothache phenomenon. If the toothache is due to tooth decay, it is recommended to have a filling in time. If it is due to pulpitis, root canal treatment is needed. If it is due to the eruption of wisdom tooth, wisdom tooth can be extracted or peri-coronal rinsing can be done. If it is due to periodontal abscess, it can be incised or periodontal scaling can be done to avoid the recurrence of toothache. Therefore, if a toothache occurs, you cannot rely on metronidazole tablets alone to solve the pain problem. You need to treat the root cause of the tooth disease and then supplement the treatment with medication. Metronidazole tablets have a time limit for use and can damage liver and kidney function, so long-term use is not recommended.