What is mixed connective tissue disease?

Patient: Description of the condition (time of onset, main symptoms, hospital visited, etc.): Patient is female, 62 years old. Often dry mouth and throat, blood sugar is not high. Severe Raynaud’s, white and purple in the ten fingers when cold Qinghai Tibetan Hospital, Department of Pharmacological Bathing, Drolma Tsetan: Mixed connective tissue disease is a connective tissue disease with mixed manifestations of lupus erythematosus, dermatomyositis or polymyositis, scleroderma, rheumatoid arthritis, etc. at the same time or not, without being able to determine which disease it is, with highly effective spotted fluorescent anti-nuclear antibodies and anti-ribonucleoprotein (n-RNP) antibodies in the blood. The disease has a good prognosis with little renal involvement and a good effect on corticosteroids. The disease is more common in women, accounting for 80% of the cases, and the onset of the disease is common around 30 years old, but it can occur in children and the elderly. Qinghai Tibetan Hospital, Department of Medicine and Bathing, Drolma Tsetan Patient: My test results are as follows. Rheumatologic Immunology Test (Routine Blood Count) 1. Specimen Type: Whole Blood Time: 2010-11-2 Test Results: WBC count 4.73 10-9/L (3.69-9.16) RBC count 4.41 10-12/L (3.68-5.13) Hemoglobin 134 g/L (113-151) Erythrocyte pressure 42.1 % (33.5-45.0 ) Mean erythrocyte volume 95.5 Fl (82.6-99.1) Mean erythrocyte hemoglobin volume 30.4 pg (26.9-33.3) Mean erythrocyte hemoglobin concentration 318 g/L (322-362) Erythrocyte volume distribution width-SD 42.9 f1 (37.0-51.0) Erythrocyte volume distribution width-CV 12.7 % (0.0- 14.9) Platelet count 149 10-9/L (101-320) Mean platelet volume 10.1 fL (7.2-13.2) Platelet body distribution width 11.7 fL (9.0-13.0) Large platelet ratio 26.6 % (13.0-43.0) * Platelet ratio 0.15 L % (0.18-0.22) Neutrophil relative value 50.9 % (50.0-70.0) Lymphocyte Relative Value 38.1 % (20.0-40.0) Monocyte Relative Value 3.0 % (3.0-10.0) *Eosinophil Relative Value 8.0 H % (0.5-5.0) Basophil Relative Value 0.0 % (0.0-1.0) 2. Specimen Type: Whole Blood2 Findings:* Weil Hematocrit First Hour 25 H ( 0-20) 3. Specimen type: whole blood 2 Results: Total T cells 74. 4 % (58.0-86.0) Auxiliary/inducible T cells 38.4 % (32.8-52.8) Cytotoxic/suppressive T cells 26.9 % (19.7-38.9) CD4+/CD8+ 1.4 (1.0-2.2) 4. Specimen type: serum Results: Tuberculin diagnostic test Negative 5. Specimen type: serum test results: alanine aminotransferase 21 IU/L (5-40) aspartate amino acid transferase 32 IU/L (8-40) total protein 80.3 g/L (60.0-83.0) albumin 48.1 g/L (34.0-48.0) globulin 32.2 g/L albumin/globulin 1.49 ( 1.00-2.00) Total bilirubin 19.5 H umoI/L (5.1-19.0) Direct bilirubin 3.5 umoI/L (0.0-7.0) Alkaline phosphatase 61 IU/L (40-150) Glutamyl transpeptidase 40 IU/L (7-50) Total bile acids 2.5 umoI/L (0.0-10.0) Cholinesterase 11.4 KU/L (4.0-12.6) Lactate dehydrogenase 192 IU/L (109-245) Prealbumin 290 mg/L (200-400) Blood glucose 5.5 mmoI/I (3.9-6.1) Urea 4.7 mmoI/L (2.9-8.2) Creatinine 51 umoI/L (45-84) Uric acid 388 umoI/L (155-428) Carbon dioxide binding 56 voI% (45-65) Calcium 2.37 mmoI/L (2.20-2.55) Phosphorus 1.12 mmoI/L (0.81-1.65) Ultrasensitive C-reactive protein 2.00 mg/L (0.00-3.00) 6. Specimen type: serum1 Results:* Immunoglobulin G 16.00 H g/L (7.51- 15.6) Immunoglobulin A 3.71 g/L (0.82-4.53) Immunoglobulin M 2.84 g/L (0.46-3.04) Complement C3 1.19 g/L (0.79-1.52) Complement C4 0.17 g/L (0.16-0.38) *Rheumatoid factor 22.5 H IU/mI (0.00-20.00 ) Anti-chain “O” 47.40 IU/mI (0.00-116.00) C-reactive protein 3.21 mg/L (0.00-8.00) 7. Specimen type: serum 4 Findings: antinuclear antibodies Positive (1:1000), mitotic type Reference: Negative (