Generally speaking, blood uric acid 495μmol/L is considered to be more serious, and treatment includes active dietary control and medication. Uric acid is the end product of purine metabolism, when the production of urate is excessive and/or the excretion of uric acid by the kidneys is reduced, the concentration of uric acid in the blood will increase, forming hyperuricemia, long-term elevation of blood uric acid may cause gout, which is considered to be related to purine metabolism disorders. The diagnostic standard of hyperuricemia is that the fasting blood uric acid level is greater than 420 μmol/L on two occasions not on the same day, and the blood uric acid 495 μmol/L has already reached a higher than the critical value of hyperuricemia, which belongs to the elevated level of uric acid, and it may induce gout, renal function damage, cardiovascular disease and so on, which is usually more serious. Patients with elevated blood uric acid need to actively adjust the dietary structure, limit or avoid purine-rich foods, and pay attention to drinking a lot of water, which can increase the excretion of uric acid. If necessary, you can also follow the doctor’s instructions to use uric acid-lowering drugs, such as benzbromarone, febuxostat and so on. If the blood uric acid 495μmol / L, it is recommended to go to the hospital in a timely manner, to check the interference of dietary factors, and if necessary, to test the blood uric acid again, combined with the underlying diseases and other conditions by a professional doctor to determine whether treatment is needed, do not self-medication.