Lenopril hydrochlorothiazide tablets can be used for diabetic patients with combined hypertension, but blood glucose, blood lipid and creatinine levels should be monitored. Lenopril hydrochlorothiazide tablets belong to the compound preparation, lenopril is angiotensin converting enzyme inhibitor, more suitable for the treatment of hypertension with diabetes mellitus patients, but can cause creatinine level increase. Hydrochlorothiazide is a diuretic, lowering blood pressure may have an effect on blood glucose and lipid levels. Patients with diabetes mellitus combined with high blood pressure, taking Lenopril hydrochlorothiazide, the various indicators that may be affected should be strengthened monitoring, if the impact is small, can continue to take. If it leads to a significant increase in blood glucose, blood lipids and creatinine levels, the drug should be discontinued in time and replaced with a different drug therapy. Adverse reactions to Lenopril hydrochlorothiazide include dry cough, thirst, headache and dizziness, hypotension, electrolyte disorders, elevation of blood glucose, blood lipids and creatinine, etc. It is contraindicated in patients who are allergic to the components of the drug, bilateral renal artery stenosis, and severe renal insufficiency. Patients with hypertension and diabetes should choose appropriate antihypertensive drugs under the guidance of physicians and monitor the adverse effects of the drugs.