The efficacy of taking vitamin E alone to lighten blemishes is not ideal, and it usually takes about 3 months to be effective, so it is best to combine it with other treatments. Vitamin E is a relatively common vitamin, and many foods have this ingredient. Oral intake of vitamin E can play an auxiliary antioxidant role, and when used with hydroquinone cream, it can make the subcutaneous pigment decompose as soon as possible, and then reduce the amount of subcutaneous pigment through the phagocytosis function of macrophages, so as to achieve the effect of lightening pigmentation spots. However, after vitamin E enters the body, it needs to be circulated through the blood before it can be applied to the local pigmented skin area, and its effective concentration is much lower at this time, so the effect will be slower, usually need to eat for about 3 months, and need to wait patiently. It is recommended that people who want to lighten their spots must do a good job of sun protection when they go out, and they can also increase the effect of lightening spots through photorejuvenation or other treatments under the guidance of doctors.