The five sensory and functional organs of the head and face are commonly called “seven orifices”, and “orifice – orifice” is connected; “orifice” is connected with cavity, and cavity – cavity is adjacent. -In the early stage, tumor lesions are hidden in the cavities and the symptoms are not obvious or even asymptomatic, but once the disease develops, the tumor will easily invade the adjacent structures. Head and neck is the place where many sensory organs and functions of human body are concentrated, such as smell, hearing, taste, vision, breathing, pronunciation, balance, etc. The five facial senses have irreplaceable importance in people’s social interactions, and all the above reasons make the treatment of eye, ear, nose and throat tumor must seize the opportunity to adopt the correct treatment method in time before the tumor causes extensive local structure and function damage, so that the patient can have better quality of life while gaining life. The treatment of eye, ear, nose, and throat tumors must be done in a timely manner before the tumor causes extensive local structural and functional damage, so that patients can have a better quality of life while gaining life. Due to the anatomical peculiarities of the eye, ear, nose and throat, tumors in one part of the body can often show the corresponding symptoms and clinical manifestations of adjacent structures. For example, a tumor at the base of maxillary sinus may invade up to the root of the tooth, resulting in toothache, and the patient may consult the dentist because of dental disease; upward development of maxillary sinus cancer may lead to proptosis and diplopia (i.e. double vision), and the patient may consult the ophthalmologist because of eye disease; maxillary sinus cancer may destroy the bone of the anterior wall and involve the infraorbital nerve, resulting in facial numbness; posterior lateral expansion and invasion of the muscles around the jaw may lead to difficulty in opening the mouth; medial development and invasion of the nasal cavity may lead to ipsilateral numbness. If it invades the nasal cavity, it will lead to ipsilateral nasal congestion. If middle ear cancer destroys the facial nerve running through the middle ear, facial palsy may occur on one side, resulting in crookedness of the mouth and inability to close the eyes on the affected side, so the patient may first consult a neurologist. Nasopharyngeal cancer is the most common head and neck tumor. The most common symptom of nasopharyngeal cancer is aspiration with blood, and because the tumor is easy to metastasize to lymph nodes, painless masses in the neck often become the reason for patients’ first consultation. The adjacent intracranial structure is temporal lobe of brain or cavernous sinus. When the tumor invades the cranium, the patient may have headache and facial numbness; because the cavernous sinus contains nerves and blood vessels related to the eye, the clinical manifestation may be proptosis, limited abduction of the eye, or even limited or no movement of the eye in all directions, so the patient may consult brain surgery or ophthalmology first. Early detection of malignant tumor is the key to treatment. Having some medical knowledge can make us take less detours in the treatment process. Due to the characteristics of cavity of otorhinolaryngology structure, there is no symptom when tumor grows in the cavity in early stage, so when we have annual physical examination, we neglect to check the five senses of head and neck. When tumor grows and breaks down, due to the rupture of blood vessels in tissues, symptoms such as blood in snot and blood in sputum will appear, such as nasopharyngeal cancer, nasal sinus cancer, laryngeal cancer, tonsil cancer, hypopharyngeal cancer and lymphoma in nasopharynx and throat; stuffy ear and hearing loss can be caused by nasopharyngeal cancer or cancer of middle ear and external ear canal; chronic purulent otitis media that does not heal for years, when there is blood in the ear discharge and ear pain at the same time, we should be alert to the possibility of middle ear cancer; sore throat and pharyngeal dissimilarity can be caused by the cancer of middle ear. When chronic purulent otitis media persists for many years, when there is blood in the ear discharge and ear pain, we should be alert to the possibility of middle ear cancer; sore throat and foreign body sensation can be seen in larynx or laryngopharyngeal tumor, while the symptoms of pharyngeal heterosensitivity are often obvious when the throat is empty. Retinoblastoma is the first among all eye tumors, and 85% of the cases are in children aged 1-7 years old, occasionally in adults. 12 or 3% of patients can have the disease successively or simultaneously in both eyes. The incidence of choroidal melanoma is second only to retinoblastoma among ocular tumors, which can have symptoms such as distortion, small size and central dark spot in early stage. The development of modern medicine has made many tumors curable, especially eye, ear, nose and throat tumors, most of which can be cured through radiotherapy and surgery, so there is no need to talk about cancer, but we still need to be vigilant and seize the treatment time to choose the right treatment plan in order to achieve the ideal clinical effect.