Endocrine drug therapy adverse effects related to different types of drugs, common glucocorticoids, thyroxine, tamoxifen and so on. 1. Glucocorticoid drugs: mainly treat hypoadrenocorticism and so on, such as hydrocortisone, prednisolone and so on. Adverse reactions such as secondary infection, centripetal obesity and peptic ulcer may occur after use. 2. Thyroid hormone: the main treatment for hypothyroidism, mostly using levothyroxine and so on. Diarrhea, palpitations, insomnia, tremor and other adverse reactions may occur after use. 3. Tamoxifen: it has anti-estrogenic effect and is mainly used in the treatment of breast cancer and ovarian cancer patients. Adverse reactions such as facial flushing, amenorrhea and loss of appetite may exist after use. Endocrine drugs can be mainly used to replace hormone secretion or antagonize hormone secretion, but also for endocrine-related tumors and other diseases. Patients are advised to use the drugs as prescribed by the doctor and to seek prompt medical attention when adverse reactions occur.