Elderly people with diabetes can take metformin and thiazolidinediones under the guidance of a doctor, there is no elderly people with diabetes to eat what is the most appropriate medicine, need to follow the doctor’s instructions for medication. 1. Metformin: commonly used drugs such as metformin, metformin hypoglycemic effect is obvious, can reduce hepatic glucose output, with the role of weight loss, the main adverse effects of gastrointestinal discomfort (diarrhea, nausea), loss of appetite and so on. 2. Thiazolidinediones: Thiazolidinediones can increase the body’s sensitivity to insulin to control blood glucose, can significantly improve insulin resistance and related metabolic disorders, type 2 diabetes mellitus and its cardiovascular complications have significant therapeutic effects, the main rosiglitazone, pioglitazone, etc., the main adverse effects of edema, weight gain. The above drugs need to be taken under the guidance of a doctor, do not take them on your own, so as not to delay the condition.