Non-small cell lung cancer-associated antigen 11.09ng/ml is more serious if elevated due to malignant tumors, while the severity due to benign diseases depends on the specific condition. Cytokeratin 19 fragment (CYFRA21-1) is the preferred tumor indicator for non-small cell lung cancer also known as non-small cell lung cancer-associated antigen, with a normal value of 0-3.3ng/ml. CYFRA21-1 value of 11.09ng/ml is higher than the normal range, which can be seen in non-small cell lung cancer, breast cancer, colorectal cancer, prostate cancer and other malignant tumors, but also in pneumonia, prostatitis, tuberculosis, chronic bronchitis and other benign diseases. In the case of malignant tumors, the elevation is more serious, and usually requires early radical surgery, radiotherapy, chemotherapy and other comprehensive treatments after thorough examination and evaluation. Elevated CYFRA21-1 in benign diseases, such as mastitis and prostatitis, is usually not serious and may improve with anti-infective treatment. Pneumonia, tuberculosis, etc. may also appear more serious conditions, such as dyspnea. It is recommended that the patient should consult the doctor in time, analyze the possible causes of the disease according to other tumor indicators, imaging tests, inflammation indicators, and clinical symptoms and signs, and cooperate with the doctor for further treatment.