Smoker’s disease is a disease first discovered by Japanese scholars in the 1950’s. It is an abnormal vascular network disease of the skull base caused by narrowing or occlusion of the major cerebral arteries. It is known as smoky disease because of the smoky vascular shadow on cerebral angiography. Although smog is a rare disease with a very low overall incidence, in recent years, due to the popularity of medical imaging technology, the detection rate of smog has been found to be on the rise. All over the country, a certain amount of smog incidence has been reported. For example, there are many smog patients from Shandong Peninsula, and some of them would ask which hospital in Qingdao is the best for treating smog. In fact, as a rare disease, many local hospitals do not know about this disease, and even some grassroots hospital personnel have never heard of it, so treatment is not even possible. Even if some local hospitals can treat smog, the success rate of surgery may not be high due to fewer cases, lack of experience and inadequate technology, and post-operative complications, sequelae and other problems. Therefore, it is recommended that patients with smog disease should go to experienced large hospitals in large places such as Beijing for treatment, so that the treatment effect is more guaranteed. At present, combined vascular bypass surgery is an effective means of treating smog disease. It is a combination of direct bypass and indirect bypass (patching), completing both procedures in the same surgery, with a two-pronged approach, establishing a perfect blood supply bypass for the patient’s brain, improving the brain blood supply comprehensively, achieving a more ideal treatment effect, which can effectively prevent the occurrence of cerebral infarction and cerebral hemorrhage, and is absolutely beneficial to smog disease patients.