The treatment of vitiligo should first determine the type and stage of the white spots, and choose the therapy and drugs according to the individual. When vitiligo is in progressive stage or generalized white spots, glucocorticosteroids can be applied systematically, especially for those with rapid development of white spots and concomitant immune diseases under stress, the use of glucocorticosteroids can stop the rapid development of rapid progressive stage. Small doses of prednisone are recommended for treatment, while topical glucocorticosteroids can be applied topically, with care that they cannot be applied over a large area, with good efficacy in progressive leukoplakia. The progressive stage of vitiligo can also take oral Chinese medicine, the efficacy is also more certain, stable stage of vitiligo can choose photochemotherapy, also can choose narrow wave ultraviolet or 308 excimer laser for treatment. If the patient applied drug therapy is not effective, and in the stable stage of limited small area white spot, especially segmental vitiligo, can consider the application of surgery and internal medicine combined therapy for treatment.