Excessive nocturia in women between 50 and 60 years of age may be caused by diseases such as diabetes, cystitis, urethritis, and overactive bladder syndrome. Patients need symptomatic treatment, which can take the form of medication, surgical treatment, and general measures to regulate. 1. Diabetes mellitus: diabetes mellitus patients will have symptoms such as polyuria, polydipsia, polyphagia, etc. Patients can use sulfonylureas such as glibenclamide tablets and glipizide tablets as prescribed by the doctor, and alpha-glycosidase inhibitor medications such as acarbose tablets and voglibose tablets can also be used. Some patients can take surgical treatment, including sleeve gastrectomy, gastric bypass and other surgical methods. 2. Cystitis: Patients with cystitis will have symptoms such as frequent urination, urgency, and painful urination, and can be treated with antibiotics such as norfloxacin capsules and ofloxacin capsules as prescribed by the doctor. Cystitis generally do not need surgery, patients should ensure adequate rest, drink appropriate water, ensure that the perineum clean. 3. Uremia: the main symptoms of patients with uremia are polyuria, irritability, thirst, patients should follow the doctor’s instructions to use 1-deamino-8-D arginine pressin, ellagic acid pressin injection and other antidiuretic drugs for treatment. The disease does not require surgical treatment. Patients should ensure adequate water intake and limit sodium intake. 4. Overactive bladder disease: patients with overactive bladder disease will have frequent urination, urinary urgency and other symptoms, patients can follow the doctor’s instructions to take oral tolterodine tartrate tablets, oxybutynin hydrochloride tablets and other M receptor blockers. Patients can also undergo surgical treatment, such as bladder enlargement, cystectomy and other surgical procedures. Nocturia in women between 50 and 60 years old should be treated symptomatically, and patients should seek medical attention to identify the cause of the condition and follow the doctor’s instructions.