Patients who are still swollen after the treatment of leg thrombosis need to go to the hospital as soon as possible to clarify the effect of treatment through imaging. If the thrombus still exists in the deep veins of the lower limbs, thrombolytic treatment with drugs such as streptokinase and urokinase or surgical treatment can be carried out. Blood clots in the legs usually need to be treated by anticoagulation, thrombolytic therapy, surgical removal of the thrombus, etc. The leg swelling does not go down after the treatment, which may indicate that blood clots still exist in the deep veins of the lower extremities. The patient can be diagnosed by venous ultrasound or CT examination, and if the thrombus still exists, it is necessary to dissolve the thrombus by streptokinase, reteplase and other medicines, and also can release the venous obstruction by surgery. It is recommended that the patient elevate the affected limb to promote venous return and actively cooperate with the doctor’s treatment.