Non-vaccination may lead to an increased risk of disease for individuals, and some diseases have no specific treatment after contracting them, and the disease may worsen or deteriorate more quickly compared to those who are vaccinated. For society, patients who do not receive vaccines may become infectious sources of prevalent diseases and endanger the health of the population because of their susceptibility. A vaccine is an active immunization preparation against infectious diseases made from pathogenic microorganisms, such as bacteria, viruses, and their metabolites, that have been artificially attenuated, inactivated, or made using genetic engineering. After vaccination, the body can be stimulated to form antibodies against diseases, thus playing a role in disease prevention. When the body is not vaccinated, there are no antibodies to pathogenic bacteria, and the body is prone to infection and disease. Vaccines in China are divided into Class I vaccines, which are free of charge, and Class II vaccines, which are other vaccines that citizens receive at their own expense and voluntarily. It is recommended to receive all vaccines as much as possible to reduce the chance of disease to a relatively low level, and vaccination is not only a personal matter, but also a matter of safety, harmony and stability of society. In addition, since vaccines are a foreign substance to the body, they may cause some uncomfortable symptoms while inducing the body’s immune system to produce protection, but most of them are self-healing and do not require special treatment. It is necessary to pay attention to any contraindications during vaccination, such as vaccine allergy, high fever before vaccination, etc.