What factors predispose to age-related purpura?

Elderly patients with certain chronic diseases, such as hypertension, diabetes and malignant tumours, are often more prone to purpura because of increased capillary fragility due to arteriosclerosis or malnutrition; collagen synthesis requires the participation of vitamin C. Vitamin C deficiency reduces the toughness of blood vessel walls and increases capillary fragility, and as we age, the body’s vitamin C content decreases progressively, a physiological change that also makes the elderly prone to purpura.