Most friends arrange long protocol treatment, then you need to start IVF treatment in the second half of your menstrual cycle. If your period is regular and ovulation is normal, your doctor will arrange for you to monitor ovulation by ultrasound on the 8th-10th day of your period, and come to the hospital roughly every 2-4 days to do ultrasound examinations and start IVF medication 1 week (7 days) after ovulation is confirmed. If your period is irregular, your doctor may arrange for you to take oral contraceptive pills. At this time, it is not deliberate for the patient couple to use contraception, but mainly to adjust your period to be able to enter the cycle smoothly to start the treatment. Generally, starting on the 5th day of your period, if the ultrasound is not abnormal, you will start taking Mafron or Daine-35, 1 tablet per day for 21 days. Follow up on day 21 of your menstrual cycle with an ultrasound and if there are no abnormalities start the IVF medication. Remember, the remaining 4-5 oral contraceptive pills must be taken as required. Usually the first round of IVF medication will be used for 14 days after entering the cycle, during which you do not need to take the medication home and inject it yourself or at the nearest clinic. 14 days later, you will come to the hospital for a follow-up visit and start the second round of medication, i.e. ovulation medication. It is best to take time off from work to start the second round, and out-of-town patients can live near the hospital to make it easier to arrange follow-up visits. The second round of medication will take about 10 days for the follicles to develop and the doctor will arrange for the night injection. After the night injection, egg retrieval surgery will be performed on the 2nd day. 3-5 days after the egg retrieval surgery, the embryos will be transferred. After the transfer, you can rest for 3 days and then you can schedule your normal work. Short and ultra-short protocols start the medication from the 2nd day of menstruation, usually about 10 days, after the follicles matured, the night shot, and the embryo transfer 3 days after the night shot. It is best to take time off from the 2nd day of menstruation. The diagram shows the general course of treatment, but each person’s situation is different. The timing of medication and follow-up visits may vary slightly from the chart. IVF treatment cycle precautions during descending and ovulation 1. All IVF patients must build a file before entering the cycle, including the second and multiple IVF patients who have not built a file cannot enter the cycle. 2. For example, if you want to have your blood drawn at 7:30 am on August 8, you must pay in advance when you come to the hospital for the previous examination, so that you can have your blood drawn at around 7:30 am on the day of the review. 3.The in vitro ultrasound is by appointment, please wait in line at the entrance of the ultrasound room strictly according to the appointment time. 4.If you need to store the medication in the test tube at 2-8 degrees Celsius, please rent an ice pack from the injection room and keep it in the parallel freezer after you go home. 5.If abnormal vaginal bleeding, abdominal distension, abdominal pain or other gynecological discomfort occurs during the IVF cycle, please inform the ultrasound physician when you review the ultrasound and adjust the medication according to your condition. 6.If fever, cough, diarrhea, rash and other medical and surgical diseases appear during the IVF cycle, you must consult the corresponding department of the general hospital in time and inform that you are currently in the IVF cycle, choose the appropriate medication for timely treatment and inform the ultrasound physician during the cycle when you review, private medication and other treatments are strictly prohibited. In case of severe high fever, trauma, major systemic diseases, etc., you need to inform our ultrasound doctor immediately after visiting the corresponding department to clarify whether you can continue the treatment for assisted conception. How to dispense Treprostin (hypotensive drug) How to dispense imported Treprostin (Dabigat): Use a 1ml syringe, pull the piston to 0.5ml, remove the needle, remove the original Treprostin needle cap, inject to its syringe mouth until full, cap the original 1ml syringe needle to drain the air and then you can give the injection. Cap the original tretinoin needle, the second day can be directly with the remaining original half of the injection (24 hours effective), occasionally delayed 1-2 hours does not have a significant impact. Domestic Treprostin needle distribution method: use 2ml syringe to draw all, play half, leave half, discard the used needle, replace the new needle and put it in the freezer, next time you can directly inject (24 hours effective), occasional delay 1-2 hours does not affect much. Precautions for medication use during the downgradation period 1.Store at 2-8 degrees Celsius, carry it with ice and refrigerator bag on the way to and from the hospital, and place it in the refrigerator freezer after returning home. 2.Injection room refrigerator is limited to half of the drug storage (half of the drug divided in our hospital). 3, both sides of the arm can be alternately injected, subcutaneous injection, the same method as the injection of vaccines, the medication process can not be interrupted, the normal use of drugs during menstruation. 4, according to the doctor’s prescription, as far as possible in the morning injection. 5. To ensure the effect of medication, try to eat less spicy and stimulating food during the treatment period, take more rest, avoid exertion and heavy sweating, and do not overheat the water temperature in the bath. Please check the time of the night injection in the medical record carefully, check whether the doctor signs, check whether the night injection medication and the medical prescription are consistent. 1.Patients who need to be injected with urotropin, Hermitage, or Rogaine, please go to the treatment room for injection after listening to the precautions. 2.On the day of the night injection, at 4:00 pm, both spouses should bring their ID cards, original marriage certificates, and copies of the laboratory tests and documents owed to the sixth floor triage desk to gather for preoperative signature (the male partner does not need to sign in the afternoon if he is a microscopic sperm extraction patient). 3.All night injections should be given in the emergency department on the first floor, The time of night injection is strictly in accordance with the time written in the medical record, and the difference between before and after should not be more than 15 minutes, if for special reasons the injection cannot be done on time, please inform the doctor at 8:00 am the next day. 5, after the night injection, do not take a hot spring, sauna or hot bath to prevent early follicle discharge. 6. The next day after the night injection, the couple should rest at home, take a bath (no tub bath) and wash their feet at night, then at 7:30 am on the day of egg collection, the couple should bring their original ID card, original marriage certificate, medical record, consultation card, a box of progesterone (at room temperature and away from light), and copies of any outstanding labs and documents to wait for the surgery on their respective floors in front of the operating room. (If you don’t have all the necessary labs or documents, we will cancel the transfer while freezing the eggs) 7. In the morning of the egg retrieval day, the woman should not drink water, soy milk, milk and other flatulent food, but can eat high calorie food such as bread, cookies, chocolate, etc. Wear open-backed clothes, long hair should be coiled and tied up, and it is forbidden to spray perfume, wax and apply irritating smelling cosmetics to avoid affecting the air in the operating room laminar flow thus affecting the quality of the embryo, no special requirements for the male diet. 8. The operation fee will be recharged into the female partner’s consultation card on the day of night injection. (Different fertilization methods, different surgical costs) The number of recharge: IVF 5500 yuan, ICSI 8500 yuan, IVF with ICSI 8500 yuan, TESA + ICSI 9500 yuan, IVF-D 12,000 yuan, microscopic sperm collection patient husband sperm collection instructions 1, after the wife into the cycle of treatment, the husband must pay attention to rest, do not stay up late, smoking, alcohol abuse Otherwise, the quality of sperm will be seriously affected. For those who live abroad, it is best to arrive one day before the egg collection, do not catch the night train! 2, IVF/ICSI abstinence 3-5 days, special circumstances according to the delivery appropriate to extend the abstinence period. 3.Ensure personal hygiene. The night before egg collection, the husband must thoroughly clean and bathe, especially the genitals and surrounding areas; clean hands before taking sperm to prevent contamination of semen. 4. On the day of egg collection, both the woman and the man should bring their ID cards and marriage certificates for inspection. 5. After the sperm retrieval, hand it over to the laboratory staff in person and do not leave immediately. If you have any questions, please feel free to consult with the laboratory staff or doctor. 6. For patients who cannot successfully retrieve sperm by masturbation, please inform the cycle nurse and doctor in advance and arrange for a male consultation in time. Precautions after egg collection 1.Please take a half hour break in the lounge on the 6th floor after egg collection, and you can eat and drink normally. 2.After half an hour, progesterone will be injected in the injection room on the 6th floor. 3. Have an ultrasound in the general ultrasound room about 2 hours after the egg collection, if the ultrasound is normal, you can go home and rest. If you experience severe abdominal pain, bright red vaginal bleeding, hematuria and other symptoms, please come to the hospital for follow-up. 4. Please come to the triage desk on the 5th floor at 2:00 pm on the 2nd day after egg retrieval (not counting the day of egg retrieval), and the nurse will arrange the ultrasound before transplantation. After the ultrasound, whether or not you are transplanted, please bring your marriage certificate, ID card, consultation card (5,500 RMB recharged in the card) and outpatient medical records with your husband at 8:30 am on the 3rd day after egg retrieval (not counting the day of egg retrieval) and wait for the pre-transplantation talk and signature in the medical office on the 5th floor. 5. Regardless of whether or not the eggs are transferred, the conversation to see the embryos on the 3rd day after egg retrieval must have both husband and wife present to sign the informed consent form for transfer or the embryo freezing agreement. By the 5th day after egg retrieval, if blastocyst transfer is needed, both couples must come to the hospital. If blastocyst transfer is not done, both couples can come to the hospital on the 6th day after egg retrieval to sign the freezing agreement. Precautions before transfer 1. Please come to the center at 8:00 am sharp for embryo transfer according to the date notified by the doctor. 2.You can have breakfast and drink moderate amount of water on that day, but do not eat flatulent food such as milk and sugar water. 3. Make sure your bladder is full before 9:30am to facilitate embryo transfer on time. If your bladder is too distended – make sure to tell the medical staff, you can urinate the right amount under the guidance, do not empty your bladder without permission. If you drink too late, your bladder will not fill up, which will affect the transfer on time, or you will have to urinate frequently after the transfer, which is not good for bed rest. 4. Before the transfer, the nurse will talk with you, tell you the embryo situation and the number of frozen embryos, and sign the “Informed Consent Form for Transfer”. If you have remaining embryos to be frozen, you must sign the Embryo Freezing Informed Consent Form and pay the embryo freezing fee and preservation fee. Please pay this fee in full before the transfer, otherwise the laboratory will not be able to freeze your embryos and you will be responsible for any adverse effects caused by this. Precautions after embryo transfer 1. You can go home after embryo transfer in bed for half an hour, pay attention to rest within 2 days, but do not stay in bed and lie flat all the time, no need to be hospitalized. 2, keep a happy mood, can go to work and do general housework, do not do heavy physical labor. 14 days no intercourse. 3.Prevent colds and fever, pay attention to dietary hygiene, prevent diarrhea, eat more vegetables and fruits, and keep bowel movements smooth. Do not drink herbal tea, do not casually use herbs to make soup, the water temperature should not be too hot when bathing, do not lie down or sit in the tub, can shower. 4.All injections or oral medications should be used strictly according to medical advice. 5.Please come to the center at 8:30 am 14 days after embryo transfer or 12 days after blastocyst transfer to take blood to determine whether you are pregnant. 6.If there is a small amount of vaginal bleeding, drip-like or a little bloody discharge after the transfer, do not panic, try to take more rest, change the oral medication of dydrogesterone to 1 time/8 hours, and then observe, if only a small amount of brown discharge continues or completely cleared after a few days, then repeat the blood test as scheduled. If the bleeding is heavy, such as heavy menstruation, you will need an outpatient visit. For more information about bleeding after transplantation, please check: 7. If you have slight abdominal distension after transplantation, if you can tolerate it, drink more water, urinate more, eat a high-protein diet, eat watermelon juice, winter melon soup and other diuretic foods, and observe the change of abdominal distension; if the abdominal distension is unbearable, you need to come to the hospital for consultation, and if necessary, puncture and abdominal fluid treatment. Application of progesterone precautions 1, the application of vaginal placement of progesterone is recommended. 2, 3-4 hours after the injection of progesterone can be hot compress injection site, pay attention to the water temperature can be moderate, to prevent burns. 3, hot compress can be used after the clean palm *** injection site to promote the absorption of drugs. 4, can be applied to the injection site raw potato slices to promote absorption, in order to prevent injection site hard knots, redness and swelling. 5.The injection site can be changed every day to prevent hard knots from arising. 6.Please have the injection in a regular medical institution. 7.If hard nodules and redness appear at the injection site, it is recommended to change to vaginal progesterone. 8.Vaginal placement of progesterone drug is better absorbed locally, while avoiding repeated hip injection injury, which is more humane and is the current trend of progesterone support medication after IVF pregnancy assistance at home and abroad. 9. Vaginal progesterone requires that the hands be cleaned in the vulva before administration, and the drug be slowly placed in the vagina, usually close to the cervix. 10.If vaginal bleeding occurs during the process of vaginal medication, it can be changed to progesterone injection for transition, and then apply vaginal medication after the bleeding is clean.