The presence of chest tightness, shortness of breath, dyspnea, panic and fast heartbeat should be suspected of cardiac system disease or pulmonary disorders, as follows: 1. Heart system disease: A portion of atypical coronary angina will manifest as the above symptoms. Atypical angina will manifest as chest tightness and shortness of breath, while typical angina will appear as suffocation, stabbing pain or pain like a knife in the precordial region. The gold standard for diagnosing angina is coronary angiography. If the persistent chest tightness, shortness of breath, dyspnea, you can consider doing angiography or coronary CT, if there is no condition, you can consider doing electrocardiography, cardiac ultrasound, can also assist in the diagnosis. 2, lung disorders: dyspnea should be considered part of the lung disorders, including pneumothorax, lung infection, pulmonary tuberculosis, may appear dyspnea, to do lung CT to clarify the diagnosis. If there is also panic and rapid heartbeat, 24-hour ambulatory ECG monitoring should be done to check the presence of arrhythmias and to determine the number and nature of the arrhythmias.