If the bladder tumor is not treated surgically, the tumor can further increase in size and the following symptoms may occur in the later stage: 1. For example, invasion of bladder muscle layer and intestine can cause chronic pain in pelvis, obstruction of intestine and even intestinal fistula. 3.Cancerous pain, when the tumor further develops, severe pain can occur, which is often difficult to relieve and progressively worsens, requiring long-term oral pain medication. 4.Difficulty in urination, when the bladder tumor further enlarges, the effective bladder capacity decreases. Patients can experience frequent urination. When the tumor further enlarges and blocks the outlet of the bladder, it can cause the symptom of difficulty in urination. 5.Secondary upper urinary tract fluid accumulation, renal function impairment or renal failure, etc. The bladder tumor further enlarges and presses the bilateral ureteral orifices or directly invades the bilateral ureteral orifices, causing ureteral atresia. The urine produced by the kidneys cannot be discharged to form hydronephrosis, resulting in anuria, which will lead to kidney failure over time.