Staying up late often from the modern medical theory, there will be melanin production and then melanin precipitation, which will lead to the growth of moles. From the perspective of Chinese medicine, staying up late has many unfavorable results. First, staying up late will lead to the decline of yang qi. When people sleep, yang qi is collected internally and yin qi is at its peak. The second is that staying up late will lead to endocrine disruption, which can lead to acne and menstrual disorders in women.