8-year-old girl diagnosed with central precocious puberty, improved after six months of treatment

(Disclaimer: This article is for general use only. To protect patient privacy, the information in the following content has been processed) Abstract: A female child, 8 years old, suddenly noticed bilateral breast enlargement in the last 6 months. She was given medication, combined with diet and exercise therapy. After half a year of treatment, the child’s height grew satisfactorily, her breasts did not get any bigger, and her physical and mental condition improved significantly. The child was treated with medication (injectable treprostinil acetate), diet and exercise therapy, The child was 8 years old and came to the clinic accompanied by her parents. The parents said that the child had found bilateral breast enlargement in February this year, but no lumps were palpable at that time, no pubic or axillary hair appeared, no significant acceleration in height and weight growth, and no other developmental signs. The child was given relevant examinations, 8 carpal bones were seen in orthopantomographs of both hands, uterine ultrasound 23×13×14mm, no obvious occupancy was seen, breast ultrasound 11mm thickened breast tissue on the left side, 11mm thickened breast tissue on the right side, disorganized breast tissue on both sides, follicle stimulating hormone 12.20IU/L, luteinizing hormone 30.81IU/L, and then admitted to the hospital for gonarelin excitation test results The result of Gonarelin excitation test was positive, and the diagnosis of central precocious puberty was confirmed. After the diagnosis was clear, the child was given injectable treprostinil acetate to suppress precocious puberty, combined with diet and exercise therapy. The diet should be light and simple, try to avoid all kinds of snacks, barbecue and foods rich in synthetic agents and coloring, and overly oily foods as little as possible, and eat more vegetables and fruits with reasonable nutrition. At the same time, increase physical activity, especially aerobic exercise, such as jogging, swimming, aerobics, etc., and ensure sufficient sleep time. It is instructed to review the outpatient clinic after six months. Half a year later, the child and parents came back to the clinic for follow-up. After the standardized medication and adjustment, together with dietary adjustment and exercise therapy, the treatment effect is still relatively good. The child’s height has grown more satisfactorily in the past six months, and his breasts have not gotten any bigger than before. After the patient explanation and psychological counseling by parents and doctors, the child no longer feels that breast enlargement is something that makes her nervous and anxious, and her physical and mental condition has improved significantly. Precautions We are glad that the child’s condition has improved after treatment. However, it is important to remind parents to pay close attention to the trend and rate of height and weight change of the child, and to compare it with other children of the same age around them. Parents should try to help their children to control the temptation of snacking because they are young. They can make some snacks at home that are suitable for their children and use healthy foods such as yogurt and fruits instead of snacks. For children’s health and nutrition products, avoid giving them to children, and if there is a need to use them, make sure to consult a doctor first. V. Personal insight Precocious puberty in children can cause the affected children to finish releasing their growth potential at a relatively early time and terminate their body growth and development in advance, and the final result may be a short final height, thus affecting their physical and mental health. Among the precocious puberty in children, the incidence of central precocious puberty is increasing and is more common in girls than in boys. Therefore, if you find signs of secondary sex characteristics development in your child, you should visit the hospital in time to clarify the specific situation.