Many patients with obstructive jaundice due to advanced malignant tumors around the jugular abdomen are unable to undergo radical surgery, and persistent jaundice not only makes the patient’s symptoms such as loss of appetite, peripheral itching, and dyspepsia more pronounced, but the persistence of jaundice can lead to bilious liver failure; prolonged hyperbilirubinemia can induce acute renal insufficiency; the intestinal mucosal barrier is damaged due to lack of bile nutrition and can lead to serious flora translocation and intestinal-derived infections. The disruption of the intestinal mucosal barrier due to lack of bile nutrition can lead to serious flora translocation and intestinal-derived infection. If the bile is not drained in time, the patient’s life is often threatened not by the tumor itself, but by the multi-organ failure caused by severe jaundice, so the necessity of palliative reduction surgery to drain the bile in patients with advanced malignant obstructive jaundice is highlighted. This procedure allows bile to bypass the obstructed segment of the bile duct caused by the tumor and enter the intestinal tract, with a definite and long-lasting effect. However, internal bile drainage performed in the open abdomen is highly invasive, and many patients cannot tolerate the procedure and have to give up internal drainage and switch to palliative external bile drainage. The widespread use of laparoscopic techniques has allowed patients with advanced malignant obstructive jaundice to achieve a reduction in jaundice without the pain of open surgery. We started to perform biliary-intestinal anastomosis using the multiport laparoscopic technique several years ago to achieve jaundice relief in patients with advanced malignant obstructive jaundice, and have completed more than 20 cases so far with satisfactory clinical results. In the past year, we have successfully completed single-hole laparoscopic biliary Roux-en-Y anastomosis and collateral anastomosis through the umbilicus, which further reduced the surgical damage and was well received and recognized by patients. Recently, after extensive review of the literature and repeated exploration and demonstration, we have created the first transumbilical single-hole laparoscopic interposition of ileal bile-intestinal anastomosis in China, which is a new way to reduce yellowness, that is, using a section of ileum to bridge the bile duct and jejunum and drain the bile, this method does not interfere with the function of high small intestine, especially suitable for patients who cannot use jejunal anastomosis. Nowadays, the operation time of single-port laparoscopic choledochotomy through the umbilicus has been shortened to about 2 hours, with minimal intraoperative bleeding, and the patient can leave the bed and eat early in 2 days after the operation, and can be discharged from the hospital in about a week. We have now successfully completed palliative reduction of jaundice in more than 10 patients using single-port laparoscopic surgery, providing a less invasive treatment for patients with advanced malignant obstructive jaundice who cannot tolerate open surgery or long-term external drainage with a tube.