The pancreas is an important digestive organ in the body, and its main function is to secrete pancreatic enzymes to digest food and regulate blood sugar levels. Acute pancreatitis is an inflammatory reaction in which the pancreatic tissue digests itself after abnormal activation of pancreatic enzymes caused by various etiologies, resulting in pancreatic edema, exudation, bleeding and even necrosis. Acute pancreatitis lacks specific symptoms, and the main manifestations at the onset are abdominal pain, abdominal distension, nausea and vomiting. The abdominal pain is mainly in the upper abdomen, and the pain can radiate to the back of the shoulder, and can be a mild degree of distension or a severe, unbearable colic. The onset of acute pancreatitis is very similar to many other abdominal diseases, such as acute cholecystitis, perforated gastroduodenal ulcer, acute appendicitis, etc. It is difficult for laymen to distinguish between them, so as long as the pain in the upper abdomen cannot be relieved within a short period of time, especially if the symptoms are gradually increasing, you should go to the hospital. Doctors diagnose acute pancreatitis not only based on the patient’s symptoms and physical examination, but also based on abdominal ultrasound, CT and other imaging examinations, as well as blood and urine laboratory tests. Blood amylase and lipase are specific laboratory indicators of acute pancreatitis, and the diagnosis of acute pancreatitis is considered to be more than 3 times the upper limit of normal value. There are three main causes of acute pancreatitis: gallstones, alcohol and hyperlipidemia. In the past 5 years, the incidence of acute pancreatitis has been increasing year by year. The predominant cause is gallstones, followed by hyperlipidemia (hypertriglyceridemia) and alcohol. People who suffer from gallbladder stones, hyperlipidemia (hypertriglyceridemia) and frequent heavy alcohol consumption are at high risk for acute pancreatitis. Therefore, regular treatment of gallbladder stones and hyperlipidemia, abstinence from alcohol and avoidance of excessive alcohol consumption are the main measures to prevent acute pancreatitis. Generally speaking, during holidays, especially during the Chinese New Year, friends and family gather and tend to eat a lot of fatty food and drink a lot of alcohol, so after the holidays is often the time when the most patients with acute pancreatitis are in the hospital. Acute pancreatitis is divided into light and heavy. Mild pancreatitis is clinically common, often self-limiting and has a good prognosis. In contrast, about 20% of patients with severe disease will develop heart, kidney, lung and other vital organ failure and pancreatic necrosis infection, the condition is dangerous and the mortality rate is as high as 20%. The treatment of severe acute pancreatitis consists of two main parts. One part is non-surgical treatment, which is aimed at the incompetence or failure of important organs such as whistle, circulation, liver and kidney, relying on the intensive care unit, close monitoring of patients’ vital signs, intensive care of patients, organ function support (e.g., whistle machine, bedside hemofiltration), and comprehensive treatment of local and systemic infections. The other part is surgical treatment for pancreatic necrosis secondary to infection. Because of the complexity and variability of the disease, the treatment of severe acute pancreatitis reflects the comprehensive strength of the hospital and the department.