Being HIV negative means that you are not infected with HIV, which means that you are in a healthy state. If you are infected with HIV, the virus enters the body and easily integrates with the body’s cells, making it difficult to remove it from the body. After HIV has invaded the body, it mainly damages the immune system, targeting CD4+ T lymphocytes, which are the most important part of the immune system, and causing the body to lose its immune function. In the late stages of the disease, untreated infected patients are prone to a variety of serious infections and malignancies that can lead to death. AIDS, also known as acquired immunodeficiency syndrome, is transmitted mainly through sexual contact, as well as through blood and blood products, or vertically from mother to child, with sexual transmission accounting for the majority of cases.