Frequent chest tightness and shortness of breath may be caused by chronic obstructive pulmonary disease, heart failure, gastroesophageal reflux and other diseases. 1. Chronic Obstructive Pulmonary Disease (COPD): Because of the airway blockage, there are airflow obstruction characteristics, and the symptoms of chest tightness and shortness of breath appear. 2. Heart failure: blood will not be able to pump to the arteries and branches in time and effectively, forming stagnation, arterial blood will be stagnated in the lungs causing pulmonary stasis. Chest tightness and shortness of breath appear. 3. Gastroesophageal reflux: Gastroesophageal reflux will be gastric juice or gastric contents, reflux to the pharynx and then inhaled into the trachea, which may cause a bronchial asthma-like reaction, resulting in airway spasm. Patients may exhibit symptoms of chest tightness and shortness of breath. Frequent chest tightness and shortness of breath can also be seen in bronchial asthma and other diseases, it is recommended to go to the hospital to clarify the cause of the disease, under the guidance of the doctor for treatment.