As a new development of lumpectomy thyroid surgery, single-port lumpectomy has the advantages of smaller scars and better cosmetic results, and is more in line with “psychological minimally invasive”. Unlike conventional lumpectomy thyroid surgery, this procedure requires only a small incision in the patient’s chest, about 1-2 cm in size, through which a mirror and lumpectomy instruments are inserted, and a small scar is left after surgery when the thyroid pathology specimen is removed through the small incision. Since there is only one access, the separation of subcutaneous tissue is also smaller, which is more in line with the concept of minimally invasive. However, because the surgical operation is performed under single-hole, single-channel conditions, the limited space on the surgical operation, the endoscope and the operating instruments enter the operating space almost parallel to each other, causing operational difficulties and mutual interference between instruments and lenses, which affects the field of view and operation. The single-hole technique is more difficult and technically advanced than the three-hole approach. Dr. Jingli Cai of the Minimally Invasive Surgery Department of the Second Hospital of Wenzhou Medical College completed the first single-port lumpectomy thyroid surgery in Wenzhou on February 18, 2011. Despite the first single-port lumpectomy thyroid surgery, the procedure went smoothly, from the start of skin cutting to the completion of thyroid removal in less than one hour, and the operation was much less difficult than expected. This is mainly due to the fact that we have routinely performed single-port laparoscopic cholecystectomy and appendectomy, and we have adopted the original “single-port, double-cannula, three-instrument” surgical method, which has not been reported in China or abroad. This method has not been reported at home or abroad, and the “single-hole, double-cannula, three-instrument” surgical method greatly reduces the interference between instruments and lenses and greatly reduces the difficulty of surgery. Therefore, we believe that, like traditional three-hole lumpectomy thyroid surgery, single-hole lumpectomy thyroid surgery can be performed routinely. Single-port lumpectomy thyroid surgery not only can completely remove the thyroid swelling, but also does not cause any adverse reactions such as pulling and pain caused by traditional cutting surgery, and has the advantages of less postoperative pain, better minimally invasive effect and better cosmetic effect, which is more in line with “psychological minimally invasive”. The patient was discharged 3 days after surgery. Single-port lumpectomy thyroid surgery is more suitable for female patients, with no scars on the neck and a transareolar incision, which results in hidden scars and excellent cosmetic results. Therefore, after the single-port lumpectomy thyroidectomy, the unsightly wound is not visible in summer, no matter how low-necked the dress is, so the advantage is very obvious. In our usual contact with patients, we often come into contact with patients with thyroid nodules. There are many patients who are suitable for treatment under lumpectomy, especially young female patients, and the use of traditional surgical methods seriously affects the aesthetics and causes a lot of psychological stress to the patients. In contrast, lumpectomy thyroid surgery is an option for female and male thyroid patients who love beauty and want to be both aesthetically pleasing and healthy. Patients with a strong cosmetic desire can undergo single-port lumpectomy thyroid surgery under the right conditions. The cost of treatment for single-port lumpectomy thyroid surgery is the same as for conventional lumpectomy thyroid surgery. Patients should go for different treatment options according to their needs and choose the one that is more suitable for them is the best. The main thing is to choose the procedure according to the severity of the disease itself. The best way to use lumpectomy thyroid surgery or single-port lumpectomy thyroid surgery is for benign thyroid tumors (simple goiter, nodular goiter or with cystic hyperplasia, thyroid adenoma, etc.) and parathyroid gland disease. As a rule, the size of the mass should not exceed 5 cm. Earlier this week, we also performed lumpectomy thyroid surgery on a patient with a 4-cm thyroid mass. The patient was admitted to an outside hospital and was told that the thyroid nodule was too large for lumpectomy and came to our hospital for treatment. In addition, for primary or secondary hyperthyroidism within the first or second degree of enlargement; low-grade malignant thyroid cancer without lymph node metastasis or local invasion within 2 cm. The surgery can also be done under lumpectomy.