Recently, there are always people who ask: “Doctor, I’ve been married for 2 years, but why can’t I get pregnant yet?” Today, we will focus on answering this question. First, let’s learn about the five major genital organs that are closely related to female fertility. 1. The first and foremost is the ovaries. Congenital dysplasia, inflammation, and tumors of the ovaries can affect egg production and development, leading to infertility. Even if there are no structural changes in the ovaries, ovulation disorders can lead to infertility. 2. Uterus: The fertilized egg has to be laid here and develop into a fetus. Many women suffer from inflammation of the uterus, adhesions, endometriosis, and uterine dysplasia, leading to infertility. The cervical opening is the first gate for sperm to enter the uterus. If tumors and inflammation occur, causing blockage and deformation of the cervix, etc., it will make it difficult for sperm to penetrate the cervix, leading to pregnancy failure. 3. Fallopian tube: It is the only channel for transporting eggs and the place where sperm and eggs are combined. Inflammation, adhesion and obstruction of the fallopian tube is one of the main causes of female infertility. 4. Vagina: Inflammatory cells and pathogens in the vagina can directly or indirectly affect the quality of sperm and lead to infertility. 5. pelvis: various inflammatory diseases and infections in the pelvis and other chronic diseases can cause lesions and dysfunctions of reproductive organs and affect conception. 6. Endocrine organ abnormalities: abnormal function of thyroid and adrenal glands, endocrine disorders, which can lead to menstrual disorders, ovulation disorders and amenorrhea, resulting in infertility. In addition to the above “hardware facilities” malfunction, there are also some “software implementation” abnormalities in the human body, which can also lead to infertility. 1. Sex hormones: Abnormal function of the hypothalamic-pituitary-ovarian axis can cause abnormal sex hormone levels, which have a significant impact on endometrial development, ovulation and egg implantation. 2, immune factors: some couples have normal reproductive organs, but they do not get pregnant. Through screening, it turns out that anti-sperm antibodies, anti-endometrial antibodies, anti-ovarian antibodies, anti-hyaluronic antibodies and other undesirable immune reactions are at work, which can kill sperm or inhibit the combination of sperm and eggs, resulting in the inability to get pregnant. 3, systemic factors: some women have serious lesions in other organs of the body (such as heart, lungs, liver, kidneys, etc.) causing physical weakness, malnutrition and various other reasons leading to fertility iso. 4, bad habits, such as, smoking, drinking may cause infertility. Of course, sex chromosome abnormalities can also lead to infertility, and these patients will have many other symptoms in addition to infertility. Because these symptoms directly affect their normal life, often their need for consultation is to solve other symptoms, and this part of women’s infertility is not part of our discussion today. Pregnancy is not only a woman’s business, it is also important that the male partner is normal or not. Women who have regular sex and have not been pregnant for more than a year without contraception are advised to seek early consultation to find the cause of infertility. Screening for infertility due to male factors is much easier compared to women, and it is recommended to check the male partner first.