In modern economic society, due to the great pressure of life and work, many people become late marriages and late childbearing; among these couples of childbearing age who are expecting mothers and fathers, 15-20% even fail to conceive successfully after one year of efforts and have infertility problems, and eventually need the help of doctors to conceive their own children. Infertility has become a common and frequent disease in our society and needs more attention and research. Thousands of years ago, our ancient great physicians put forward the idea in the Yellow Emperor’s Classic of Internal Medicine that “the sage does not treat the disease before it occurs”, emphasizing the prevention of disease before it occurs and taking measures to prevent it before it occurs. Today, we will discuss with you some common problems we encountered in our clinical practice, and discuss some considerations during the planning of conception to improve the chance of natural conception. The first is pre-conception preparation. Smoking and alcohol consumption can affect the production of male sperm and female eggs, and have a significant negative effect on fetal development, and should be avoided at all costs. Before preparing for conception, both partners should temporarily avoid occupational hazards and promptly transfer from jobs where they may be exposed to harmful substances such as lead, mercury, benzene, nickel, ammonia, radiation, isotopes and electromagnetic waves. Eat more vegetables and fruits to get enough vitamins, and eat oysters and other seafood to get enough zinc and other trace elements. The sperm production cycle of men is about seventy days, so the pre-conception preparation should be more reasonable from three months to six months. Next is to grasp the timing of conception. The process of fertilization is that the male ejaculates semen into the woman’s vagina during sexual intercourse, and the sperm relies on the tail swinging through the cervix into the uterus and then into the fallopian tube, eventually meeting the egg in the abdomen of the female fallopian tube and penetrating the egg to form a fertilized egg and complete fertilization. Two conditions are needed to achieve precise control and accurate completion of fertilization: one is to detect the timing of ovulation, and the other is to have a sufficient number of good sperm at this critical moment. During her reproductive age, a woman expels one mature egg per month, which survives for less than 24 hours; while sperm survives for a longer period of time in a woman’s body, usually up to about 3 days. Therefore, we recommend women to monitor ovulation at home by simple means such as basal body temperature or ovulation test strips, and to start sexual intercourse 1-2 days before ovulation, and have intercourse every other day during ovulation; and abstain from sex for about a week before the first sexual intercourse, so that the number and vitality of sperm exist in a better balance. The best time to conceive is to arrange sex accurately on the date of ovulation. Finally, we also need to pay attention to the chances of natural conception. Healthy men produce more than 100 million sperm per day, while women develop and mature only one egg per month, and expel about 12 mature eggs a year, which means there are about 12 chances of conception. It is estimated that the monthly conception rate of a normal couple is 20-25%, 75% in half a year and about 90% in a year, and the peak fertility rate for both men and women is at the age of 24, and then fertility declines with age. Therefore, couples who have not yet succeeded in conceiving after one year of preparation are advised to go to a specialized hospital for relevant examinations and to obtain medical help.