AIDS-phobia is a strong fear of AIDS with anxiety, depression and other psychological disorders. The main clinical treatment for AIDS-phobia is pharmacotherapy and psychotherapy. Medication can choose benzodiazepines, such as alprazolam, lorazepam, eszopiclone and other drugs to control anxiety, the treatment effect is relatively fast, but the use of drugs should be applied in small doses for a short period of time. Antidepressants can also be applied, mainly 5-hydroxytryptamine reuptake inhibitors, such as paroxetine, fluoxetine, sertraline, escitalopram and other drugs. Non-benzodiazepine anxiolytics, such as buspirone and tandospirone, can also treat Islamophobia. In addition psychotherapy is also effective as a treatment option for Islamophobia, such as cognitive behavioral therapy, which focuses on improving the patient’s irrational cognition and reconstructing the cognitive system. Supportive psychotherapy is more common and focuses on giving patients support, understanding, and care to help them get through painful emotional experiences. In addition, relaxation training, family therapy and other therapies are also used in clinical practice and have been recognized for their therapeutic effects.