Menstruation does not come, the causes of breast swelling and pain include breast disease, soft tissue abnormalities, hormonal changes, as follows: 1, breast disease: such as breast hyperplasia, mastitis, cystic lesions of the breast, breast cancer and other causes of menstruation does not come, once the above-mentioned disease attacks, can trigger the breast area swelling and pain; 2, soft tissue abnormalities: soft tissue abnormalities in the breast area, such as inflammation of one side of the axillary lymph nodes discharged to one side of the breast, so that the breast 3, hormonal changes: menstruation does not come, but the body hormone level has begun to change, estrogen has changed, causing vasoconstriction and diastole, inducing vasodilation in the breast area or breast gland hyperplasia, causing swelling and pain in the breast area.