Urticaria is mainly mast cell activation caused by edematous masses on the surface of the skin and mucous membranes, topical medications are mainly symptomatic to relieve itching, there is no clear therapeutic significance, such as glycerite lotion, mometasone furoate cream, etc., as follows: 1. Glycerite lotion: glycerite lotion is mainly composed of glycerite and zinc oxide, coated with the affected area, has a cool, anti-itching, astringent effect, for hives caused by itchy skin symptoms have a better improvement, it should be noted that should be avoided contact with the eyes, nose and other mucous membranes. 2. Mometasone furoate cream: mometasone furoate is a kind of glucocorticoid, with anti-inflammatory and anti-allergic effects, can be used for hives, eczema, etc., need to be the main skin burning sensation, tingling sensation and other adverse reactions may occur. Skin breakage is prohibited, pregnant women, lactating women should be used with caution. Due to the existence of certain adverse reactions to the above drugs, all need to be used under the guidance of a doctor, it is recommended that patients with urticaria seek medical treatment in a timely manner.