When the situation of diabetic patients with sore legs occurs, the causes are different, and the treatment methods are also different. There may be physiological factors, such as excessive exercise, etc.; there may also be pathological factors, such as diabetes combined with lower limb arterial vasculopathy, etc., which can be treated with glycemic control or plaque stabilization. 1. Physiological factors: if diabetic patients have excessive exercise leading to excessive accumulation of lactic acid, it is easy to cause calf soreness, so there may be diabetic patients with sore legs, it is recommended to pay more attention to rest after exercise. 2. Pathological factors: such as diabetes combined with lower limb arterial vascular disease, can choose to control blood glucose treatment, such as active control of blood glucose can delay the occurrence of vascular complications in the lower limbs, if necessary, switch to insulin, to achieve the purpose of controlling blood glucose; can also choose to stabilize plaque treatment, such as under the guidance of a physician to take a statin class of drugs, such as atorvastatin calcium, and so on. When diabetic patients’ legs are sore and swollen, they should consult a doctor in time and find out the cause of the disease, and carry out targeted treatment under the guidance of the doctor, so as to avoid delaying the condition.